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Bio-Meso PDRN Spicule Facial Treatment in Ashford, Surrey

At Autumn Harmony, I am thrilled to be among the first clinics in the local area to offer the GENOSYS Bio Meso PDRN Spicule Treatment — one of the most advanced skin regeneration treatments available in professional skincare today. Powered by BIO-MESO™ technology and millions of natural spicules, Bio Meso is a premium, needle-free alternative to Microneedling that delivers deep skin renewal, collagen stimulation, and visible rejuvenation — with minimal downtime. If you're looking for next-level results without needles, this is it.

Based at Heather's Beauty Box Salon in Ashford, Surrey TW15, near Heathrow, I offer this treatment to clients across Ashford, Feltham, Sunbury, Staines, Shepperton, and surrounding areas.

What Is Bio Meso?

Bio Meso is an advanced professional skin treatment that uses natural spicules — microscopic needle-like structures derived from freshwater sponges — to create microchannels in the skin's outer layer. This process, known as bio-microneedling or liquid microneedling, stimulates the skin's natural repair response without the use of needles or visible injury.

The treatment is powered by the GENOSYS Bio-Meso PDRN Expert Ampoule 60000 — a professional-grade ampoule packed with PDRN, panthenol, 5 ceramides, 8 anti-ageing peptides, and 9 growth factor peptides, all delivered deep into the skin via spicule technology.

Once applied, spicules remain embedded in the skin for approximately 24–72 hours, gradually breaking down through natural skin shedding — continuing to work long after you leave the clinic.

What Can Bio Meso Help With?

This treatment is ideal if you are concerned about:

It is particularly well suited to clients who want the regenerative benefits of Microneedling but prefer a completely needle-free approach.

Pricing

Treatment Clinic Mobile
Bio Meso Treatment — Single Session £165 £195
Bio Meso Treatment — Course of 3 £395 £485

Booking a Course of 3 saves you £100 at the clinic (vs. £495 individually) or £100 on mobile (vs. £585 individually). The course of 3 must be used within 4 months of the purchase date, with a minimum of 4 weeks between each session to allow the skin adequate time to recover and respond.

Preparing for Your Treatment

  • Sun exposure: Avoid prolonged sun exposure and sunbeds for at least 2 weeks before your appointment, and for 2 weeks after.
  • Active skincare: Pause retinoids and strong acids (AHAs, BHAs, vitamin C) for at least 7–14 days before treatment.
  • Tanning injections: The use of nasal tanning injections is strictly prohibited at all times and will prevent treatment from going ahead.
  • Medication: Please inform me of any medication you are currently taking, or have taken within the past two weeks, prior to your appointment.

Is This Treatment Right for Me?

Bio Meso is suitable for most skin types and concerns. A consultation is required before your first treatment so I can assess your skin, review your current skincare routine, and confirm suitability.

Treatment cannot be performed if you have any of the following:

  • Skin cancers or precancerous lesions
  • Keloid formation or a history of rapid scarring
  • Collagen vascular disorders, including scleroderma
  • Unstable diabetes or impaired wound healing
  • Chronic inflammatory skin conditions such as eczema or psoriasis
  • Autoimmune conditions that affect the skin, or current steroid therapy
  • Blood or platelet clotting disorders
  • Active skin infections — bacterial, viral, or fungal
  • Recent sunburn or active tanning
  • Broken, damaged, or injured skin in the treatment area
  • Raised moles, warts, or other elevated lesions within the treatment area
  • Surgical or trauma-related scars less than 6 months old
  • Open wounds or broken skin
  • Current use of retinoids or strong acids (stop at least 7–14 days before; do not resume for at least 14 days after)
  • Use of Isotretinoin (Accutane), chemotherapy, or radiation therapy within the past 2 weeks
  • Pregnancy or breastfeeding

If you are unsure about any of the above, please get in touch before booking — I am happy to advise.

What to Expect During Your Treatment

Your Bio Meso treatment follows a carefully structured protocol, recommended every 4 weeks for optimal results. Here's what your appointment looks like:

  1. Cleanse & Prepare — Your skin is thoroughly cleansed using the GENOSYS Skin Defender Lip & Eye Makeup Remover followed by the GENOSYS Snow O₂ Oxygen Cleanser. Both are available to purchase as part of your ongoing skincare routine.
  2. Pre-Treatment Mask — A professional exfoliating CO₂ treatment mask is applied to further prime and prepare the skin, maximising absorption of the active ingredients to follow.
  3. Bio Meso Treatment — The GENOSYS Bio-Meso PDRN Expert Ampoule 60000 is applied across the face and gently worked into the skin, embedding millions of spicules that stimulate renewal and drive PDRN, peptides, and ceramides deep into the skin.
  4. Soothing Mask & SPF Finish — A calming GENOSYS Skin Reboot PDRN Mask is applied to soothe and hydrate the skin, followed by either the GENOSYS Multi Sun Cream SPF40 or Ultra Shield SPF50+ to protect your freshly treated skin before you leave the clinic.

What Happens After Your Treatment?

Bio Meso is a minimal-downtime treatment — most clients return to normal activities the same day. Here's what to expect:

  • Days 1–2: Mild redness or tingling as the skin's micro-circulation and cell activity is stimulated — completely normal
  • Days 3–5: Skin turnover accelerates; some mild flaking or peeling may occur. Keep the skin well moisturised and allow it to shed naturally
  • Days 6–10: Skin appears smoother, brighter, and more even in tone
  • Days 11–15: Collagen synthesis increases; firmness and elasticity continue to improve

To support your skin at home after treatment:

  • Avoid sauna, steam room, swimming pools, and extreme heat for 5 days
  • Avoid active skincare ingredients (retinoids, AHAs, BHAs, high-strength vitamin C) for 10 days
  • Do not scrub or exfoliate until any flaking has fully resolved
  • Focus on hydration and barrier repair for 7 days
  • Avoid makeup for the first 24 hours — a tinted SPF is a good alternative if needed
  • Mild itching is a normal post-treatment response — gently pat the skin, avoid scratching

Recommended Home Care Products

The following GENOSYS products are recommended to support your skin before, during, and after your Bio Meso programme. This list is not exhaustive — your home care routine will be tailored to your skin at consultation:

Browse the full GENOSYS skincare range, our curated Anti-Ageing Skincare collection, or visit the GENOSYS brand page to learn more.

The Science Behind Bio Meso

Spicules are microscopic, needle-like structures extracted from freshwater sponges. When applied to the skin, they create microchannels in the skin's outer layer, triggering a mild controlled response that stimulates collagen production, accelerates cell renewal, and dramatically enhances the absorption of active ingredients. The effect is clinically equivalent to approximately 1.0mm Microneedling stimulation — without a single needle.

The Three-Step BIO-MESO™ Delivery System

What makes the GENOSYS Bio-Meso treatment uniquely effective is its patented three-stage delivery system, designed to maximise both spicule performance and active ingredient penetration:

  1. High Purity Spicule Extraction — natural needle-like structures from freshwater sponges are extracted to the highest purity standard, forming precise micro-channels in the skin's outer layer to open the pathway for active ingredients
  2. PDRN Phytosome Encapsulation — PDRN (Polydeoxyribonucleotide) is chemically bound to phospholipids, forming phytosomes that are optimised for skin absorption — ensuring the active ingredient reaches where it is needed most
  3. Advanced Spicule Coating — PDRN-loaded phytosomes are coated onto 3rd generation cog spicules, enhancing both skin compatibility and depth of penetration for superior results

What sets the GENOSYS Bio-Meso ampoule apart is its exceptional formulation and spicule density:

  • 300,000–360,000 spicules per 1ml — significantly more than typical products
  • 0.9–1.08 million spicules per full treatment application
  • Dermal absorption extent 2.935× greater than control products
  • Dermal absorption rate 6,000× greater than control products

Key Active Ingredients

PDRN (60,000ppm) — derived from salmon DNA with 95% similarity to human DNA. PDRN stimulates cell turnover and skin regeneration, enhances collagen and elastin synthesis, reduces inflammation, and helps soothe damaged or sensitised skin.

Panthenol (10,000ppm) — provides deep hydration and barrier reinforcement, calming the skin and protecting against external aggressors.

5 Ceramides + 8 Anti-Ageing Peptides + 9 Growth Factor Peptides — work together to boost elasticity, improve skin tone, target fine lines and blemishes, and deliver firming and revitalising benefits throughout the skin.

Clinical Results

In a clinical study of 9 females (aged 48 ±8), the GENOSYS Bio-Meso PDRN Expert Ampoule 60000 demonstrated the following improvements:

  • Periorbital wrinkles reduced by 4.8% after 1 week, 5.75% after 2 weeks, and 7.45% after 4 weeks
  • Skin hydration improved by 18.96% after 1 week, 32.82% after 2 weeks, and 52.25% after 4 weeks
  • Skin elasticity improved by 5.68% after 1 week, 14.96% after 2 weeks, and 19.86% after 4 weeks
  • Skin tone improved by 1.06% after 1 week and 1.69% after 2 weeks
  • Skin exfoliation rate 29% higher than untreated at 1 week and 20% higher at 2 weeks

GENOSYS Bio Meso before and after — visible improvement in blemishes and skin tone

GENOSYS Bio Meso PDRN Spicule Treatment — before and after. Results shown are from clinical use of GENOSYS professional products. Individual results may vary.

FAQs About Bio Meso

Is Bio Meso the same as Microneedling?

Bio Meso is often called liquid microneedling or bio-microneedling because it produces a clinically similar effect to approximately 1.0mm Microneedling — but without any needles. Natural spicules create microchannels in the skin's outer layer, stimulating collagen and delivering active ingredients deep into the skin.

Does the treatment hurt?

Most clients experience mild tingling or a pricking sensation during and after treatment. This is completely normal and typically settles within 1–3 days.

Is there any downtime?

Bio Meso is a minimal-downtime treatment. You may experience mild redness and tingling for 1–3 days, and some mild flaking around days 3–5 as the skin renews. Most clients return to normal activities the same day.

How many sessions will I need?

Results are visible from a single session, with skin appearing smoother and brighter within 6–10 days. For optimal results — particularly for fine lines, pigmentation, and firmness — a course of treatments every 4 weeks is recommended.

Is there a saving for booking a course?

Yes — a Course of 3 saves you £100 compared to booking three individual sessions (£495 clinic / £585 mobile). The course must be used within 4 months of purchase, with a minimum of 4 weeks between each session.

Can I wear makeup after Bio Meso?

It is best to avoid makeup for at least 24 hours post-treatment. A tinted SPF is a good alternative if you need some coverage on the day.

Can Bio Meso be combined with other treatments?

Yes — Bio Meso pairs well with Bespoke Facials and Chemical Peels as part of a wider skin programme. Combination timing will always be discussed at consultation.

Do I need a consultation before my first treatment?

Yes — a consultation is required before your first Bio Meso treatment to assess your skin, review your skincare routine, and confirm suitability.

What skincare should I use at home after treatment?

Focus on hydration and barrier repair for the first 7 days. Avoid retinoids, AHAs, BHAs, and exfoliants for at least 10 days. See the Recommended Home Care Products section above for specific product suggestions.

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